Within the discussions at the United Nations Commission on International Trade Law, countries are working toward the creation of a multilateral instrument that could be crafted so as to reform investor-state dispute settlement (ISDS). Recognizing that initiative, and broader support for reform of international investment law, this paper proposes the creation of a Framework Convention on Investment and Sustainable Development (the “Framework Convention”). The Framework Convention would provide States a practical, efficient, and flexible mechanism to move beyond the current investor-protection centered system, and to allow countries and other stakeholders to address the challenges and advance the objectives of sustainable development by developing and implementing new approaches to the support and regulation of transnational investment.